Log In

INVEST IN ONCOLYZE TODAY!

Treating Cancer by Exploding Cancer Cells

Oncolyze is a preclinical stage biotechnology company which is developing an innovative new cancer drug that selectively attacks cancer cells by causing them to explode and die while leaving normal cells intact.

This Reg A+ offering is made available through StartEngine Primary, LLC. This investment is speculative, illiquid, and involves a high degree of risk, including the possible loss of your entire investment.

$704,518.43 Raised



Offering Circular | Selected Risks Related to this Offering | SEC EDGAR Page


REASONS TO INVEST


  • Our lead drug candidate OM-301 has been shown to selectively kill cancer cells by targeting a cell surface protein unique to cancer without the drug having to enter inside the cell, potentially enabling highly effective treatments with fewer side effects.


  • We are led by a team highly skilled in the life sciences across drug discovery, development, and commercialization with over 200 years of combined experience in biopharma. Our advisors are amongst the top thought leaders in leukemia research and therapeutics.


  • We have already raised over $2 million to date. Data from our preclinical trials has demonstrated that OM-301 has the ability to kill human leukemic cells and leukemic stem cells implanted in mice, without suppressing normal blood formation in the bone marrow. Now, we plan to advance this lead product toward clinical trials.





the pitch

Our mission is to provide cancer patients with a novel therapy that selectively attacks cancer cells and pokes holes in their cell membrane, causing these cancer cells to explode and die while leaving normal cells intact. We will start by targeting acute myeloid leukemia (AML), an aggressive type of blood cancer with a low survival rate. With Orphan Drug Designation granted by the FDA, multiple patents filed, and promising trials in mice completed, we are ready to advance our lead product into clinical trials.



OVERVIEW





Developing Technology to Explode Cancer Cells

Cancer is the second leading cause of death globally, killing 10 million patients each year. Oncolyze’s lead drug candidate, OM-301 targets a protein that is found on the cell surface of multiple solid (e.g., pancreatic, ovarian, breast, prostate) and blood (e.g., like leukemia, lymphoma) cancers, but is not seen on the surface of normal cells. OM-301 selectively destroys cancer cells by a mechanism we have termed  “poptosis” (referring to cell bursting, also known as lysis/necrosis) while leaving normal cells intact. One of the deadliest blood cancers is acute myeloid leukemia (AML). Patients with AML have only a 1 in 4 chance of living for 5 years after diagnosis. Our first clinical trial will focus on treating patients with AML. With our team of highly experienced leaders in biopharma and advisors from some of the world’s top cancer institutes, we aim to bring new treatment options to millions of cancer patients.

THE PROBLEM & OUR SOLUTION


Current Treatments Only Give AML Patients a 25% Survival Rate

Anticancer chemotherapy drugs need to go inside cancer cells and then attack them internally, causing them to self-destruct from within. However, chemotherapy has effects that are not specific to cancer cells; as a consequence, normal cells are also killed causing terrible side effects. Although targeted anticancer therapies are designed to interact with specific targets on cancer cells, the targets may also exist on normal cells, and often these drugs only block proliferation of the cancer cells without killing them.


OM-301 combines the best of chemotherapy + targeted therapy. The targeting piece finds a cancer-specific protein that sits on the external surface of nearly all cancer cells (HDM2) but not normal cells. Once OM-301 finds HDM2 and anchors, the active piece pokes holes in the surface and selectively kills the cancer cells almost instantly while sparing the normal cells.

THE MARKET & OUR TRACTION


Promising Preclinical Research and a Massive Market Need

The American Cancer Society projects approximately 20,000 new cases of AML each year in the US. The current annual cost for AML treatment ranges up to $100,000. This translates to a potential total addressable market of $2 billion for AML in the US alone.

We have been granted Orphan Drug Designation by the FDA, which confers significant market protection upon approval of the drug. In addition, we have a growing portfolio of US and international patent applications. Exciting pre-clinical data has already demonstrated that OM-301 has the ability to kill human leukemic cells and leukemic stem cells implanted into mice, an extremely important step on the pathway to testing the drug in patients with AML.

* The above video is an animation illustrating the mechanism of action.


Our leadership team has over 200 years of combined biopharma industry experience. Our advisors are amongst the world’s top thought leaders in leukemia research and therapeutics.

WHY INVEST


Bringing Hope to Millions of Cancer Patients

The estimated total annual economic impact of cancer amounts to more than $1 trillion globally. Our mission is to bring forward a new, effective drug with fewer side effects to treat the most aggressive and deadly cancers. We have built an exceptional team of leaders and advisors in biopharma and cancer research, achieved FDA Orphan Drug Designation, filed multiple patents for our technology, and executed highly promising preclinical trials in mice. Join us as we give hope to cancer patients and their families everywhere.


AN OFFERING STATEMENT REGARDING THIS OFFERING HAS BEEN FILED WITH THE SEC. THE SEC HAS QUALIFIED THAT OFFERING STATEMENT, WHICH ONLY MEANS THAT THE COMPANY MAY MAKE SALES OF THE SECURITIES DESCRIBED BY THE OFFERING STATEMENT. IT DOES NOT MEAN THAT THE SEC HAS APPROVED, PASSED UPON THE MERITS OR PASSED UPON THE ACCURACY OR COMPLETENESS OF THE INFORMATION IN THE OFFERING STATEMENT.



THE OFFERING CIRCULAR THAT IS PART OF THAT OFFERING STATEMENT CAN BE FOUND HERE


CROWDCHECK VERIFIED REPORT CAN BE FOUND HERE.



THE OFFERING MATERIALS MAY CONTAIN FORWARD-LOOKING STATEMENTS AND INFORMATION RELATING TO, AMONG OTHER THINGS, THE COMPANY, ITS BUSINESS PLAN AND STRATEGY, AND ITS INDUSTRY. THESE FORWARD-LOOKING STATEMENTS ARE BASED ON THE BELIEFS OF, ASSUMPTIONS MADE BY, AND INFORMATION CURRENTLY AVAILABLE TO THE COMPANY’S MANAGEMENT. WHEN USED IN THE OFFERING MATERIALS, THE WORDS “ESTIMATE,” “PROJECT,” “BELIEVE,” “ANTICIPATE,” “INTEND,” “EXPECT” AND SIMILAR EXPRESSIONS ARE INTENDED TO IDENTIFY FORWARD-LOOKING STATEMENTS, WHICH CONSTITUTE FORWARD LOOKING STATEMENTS. THESE STATEMENTS REFLECT MANAGEMENT’S CURRENT VIEWS WITH RESPECT TO FUTURE EVENTS AND ARE SUBJECT TO RISKS AND UNCERTAINTIES THAT COULD CAUSE THE COMPANY’S ACTUAL RESULTS TO DIFFER MATERIALLY FROM THOSE CONTAINED IN THE FORWARD-LOOKING STATEMENTS. INVESTORS ARE CAUTIONED NOT TO PLACE UNDUE RELIANCE ON THESE FORWARD-LOOKING STATEMENTS, WHICH SPEAK ONLY AS OF THE DATE ON WHICH THEY ARE MADE. THE COMPANY DOES NOT UNDERTAKE ANY OBLIGATION TO REVISE OR UPDATE THESE FORWARD-LOOKING STATEMENTS TO REFLECT EVENTS OR CIRCUMSTANCES AFTER SUCH DATE OR TO REFLECT THE OCCURRENCE OF UNANTICIPATED EVENTS.

ABOUT

HEADQUARTERS
845 UN Plaza, 61B
New York City, NY 10017

Oncolyze is a preclinical stage biotechnology company which is developing an innovative new cancer drug that selectively attacks cancer cells by causing them to explode and die while leaving normal cells intact.

TEAM

Steven J. Evans, MD

Steven J. Evans, MD

Founder, CEO and Director

Dr. Evans founded the company and has served as our Chief Executive Officer since 2016 and Director since 2011. Dr. Evans obtained his MD from the New York University School of Medicine, completed his fellowship in Cardiovascular Disease and Electrophysiology at Cedars-Sinai Hospital, and in the course of his career became both an experienced entrepreneur and a leading strategic advisor in the life sciences area with 25 years of experience working for clients including Biosense, Johnson & Johnson, Medtronic, Guidant, Impulse Dynamics, St. Jude, and Atricure, and consulting for venture funds focused on new medical technologies. His expertise spans scientific assessment, clinical research, market analysis, regulatory and reimbursement evaluation, and C-level experience. He is the co-inventor and co-founder of ImaCor Medical Technologies; as CEO of ImaCor, he secured a $5 million venture investment in 2004. He led ImaCor through R&D, clinical trials, product manufacturing, a second $5 million round in 2006, and FDA clearance; the company is currently in sales. From 2007 to 2015, Dr. Evans, as CEO of Althera, led the company through a critical restructuring, a $6 million+ bridge financing, the formation of a US subsidiary, and the build-out of strong management and medical teams. Althera exited via a stock swap in 2015 and is currently in very successful clinical trials.

Alex Stojanovic, PhD

Alex Stojanovic, PhD

Chief Operating Officer

Dr. Stojanovic joined Oncolyze in 2019 as COO. He brings 16 years of global consulting and operational experience in the life sciences and has worked or consulted for more than 50 public and private companies throughout that time.

Since 2019, he has served as Managing Partner at The Naissos Group, where he has advised life science companies across the United States, Europe, Asia, and Australia on various operational, commercial and corporate topics. From 2013 to 2018, he was VP of Business Development & Commercial Operations at Phosphagenics, an Australian pharmaceutical company, where he played a key role in overhauling the corporate brand, vision and strategy, to instill investor confidence in a turnaround situation and enable a $19 million financing. He guided the company to reposition R&D efforts, leveraging a proprietary drug delivery technology, from topical to injectable, resulting in more than half a dozen new assets and a major partnership with Terumo. Prior to that, from 2011 to 2013, he was Head of New Products Marketing at Grunenthal, where he led commercial development of pipeline entities from Phase 1 to 3. Earlier in his career, from 2006 to 2011, he was a Consultant with ZS Associates for six years.

He was a NIH Postdoctoral Fellow at the Center for Drug Discovery, Northwestern University. He earned BS degrees in both Chemistry and Cell Biology at the University of Illinois and a PhD in Pharmacology & Toxicology at Dartmouth College.

Larry Altstiel, MD, PhD

Larry Altstiel, MD, PhD

Chief Scientific Officer

Dr. Altstiel joined Oncolyze in 2019 as CSO. Before joining Oncolyze, he served as Chief Medical Officer (2015 to 2018) and Executive Vice President (2016 to 2018) of vTv Therapeutics Inc. He served as the CEO of Provectra Biotherapeutics, an early-stage biotechnology company developing novel gene therapy for neurodegenerative diseases, from 2013 to 2015, and was its founder. He was responsible for all of Provectra’s product development activities, while leading Provectra toward commercializing products based upon its proprietary gene therapy technologies. From 2007 to 2013, he served as VP of Neuroscience Clinical Development and Neuroscience Therapeutic Area Clinical Lead, at Pfizer Inc. His principal responsibilities were directing PGRD Neuroscience Research Unit clinical research, which included governance, operational and budgetary responsibilities for: preclinical biology and first in human studies; supervising of transitional medical plans and related external alliances; supervising clinical teams conducting early phase clinical research from translational medicine through proof of concept and subsequent Phase 3 clinical trials.

Dr. Altstiel was a NIH Postdoctoral Fellow at The Biological Laboratories, Harvard University. He earned a BS in Chemistry / Physics at the University of Illinois, a PhD in Cell Biology, Virology and Physical Chemistry at The Rockefeller University and a MD at The University of Miami, Miller School of Medicine.

John Abeles, MD

John Abeles, MD

Co-Founder, Chief Corporate Development and Strategy Officer and Director

Dr. Abeles has served as our Chief Corporate Development and Strategy Officer since 2018 and as a director since 2011. Dr. Abeles received his MD and a degree in Physiology and Pharmacology from the University of Birmingham, England. He practiced medicine in London and Connecticut, and has held senior medical positions with Sterling Drug, Pfizer and USV. In 1975, he became the first full-time Wall Street healthcare analyst with MD qualifications, at Kidder Peabody.

In 1980. Dr. Abeles formed MedVest Group, a biomedical consulting firm, and later Northlea Partners, his family office. Dr. Abeles has promulgated, and sometimes founded, many early-stage biomedical companies, several of which have been acquired and/or become public companies.

He has served as an Advisory Board Member of the College of Chemistry, University of California, Berkeley, an external member of the SPARK program at Stanford University, and an Advisory Board member of the Higuchi BioSciences Institute at the University of Kansas. He is a Fellow of the Royal Society of Medicine, London. He is a member of the board of several healthcare non-profit organizations in the U.S. and Israel and is active in sponsoring the arts and several charities.

Rosemary Mazanet, MD, PhD

Rosemary Mazanet, MD, PhD

Director

Dr. Mazanet has been an investor, executive and expert in healthcare for more than 25 years. A trained Oncologist, she was intimately involved with the development of Neupogen (among other product candidates) and the Cell Therapy program at Amgen, where she was head of Oncology Clinical Research from 1992 to 1998. After moving to the investment world in 1998, she helped to manage the Oracle Partners Biotech portfolio which had very profitable years from 1998 to 2003. Since 2004, in her role as an investor and a consultant, she has founded companies (Breakthrough Therapeutics, Inc), acted as interim management (Interim CEO, Access Pharmaceuticals OTC: ACCP; Interim CEO, Diabetes America, Inc., CMO, NKT Therapeutics), and corporate advisor to many biotechnology companies, funds and firms. She serves/has served as a director of public (GTI, Inc., (NASD: GTXI), Aksys LTD. Access Pharmaceuticals) and private (Actinium Pharmaceuticals, Amorcyte, Cellumen, Patriot Care) companies.

For the past ten years, she has been a Trustee and Member of the Executive Committee for the School of Medicine and Health System at the University of Pennsylvania. She remains licensed to practice medicine in several states.

James L. Foght, PhD

James L. Foght, PhD

Director

James Foght has been an Independent Director with Oncolyze since 2016. Dr. Foght obtained his PhD from the University of Illinois, having done research in Organic Chemistry, Biochemistry, and Microbiology. He was Co-Founder and Managing Director for DuPont Pharmaceuticals Europe, Africa and Middle East, after which he was a Co-Founder and Co-Director of the first life science investment banking group at Kidder Peabody. He was a Co-Founder and President of Vector Securities, and a Co-Founder of Deerfield Partners Hedge Fund, one of the most successful hedge funds in the life sciences. He serves on the Boards of Cambridge Antibody (UK), Acrux Limited, and Pinnacle Biologics.

Alexander Zukiwski, MD

Alexander Zukiwski, MD

Director

Alexander Zukiwski has been an Independent Director with Oncolyze since 2017. Dr. Zukiwski has more than 22 years of experience in global drug development and has supported the clinical evaluation and registration of many successful therapeutic agents, including Taxotere®, Xeloda®, Procrit®/Eprex®, Velcade®, Yondelis®, and Doxil®, and currently serves as the Chief Medical Officer of CASI Pharmaceuticals. He was Chief Executive Officer and Chief Medical Officer of Arno Therapeutics and has been a Director of Arno Therapeutics since 2014. Prior to Arno in 2007, he served as Chief Medical Officer and Executive Vice President of Clinical Research at MedImmune. Prior to MedImmune, Dr. Zukiwski held several roles of increasing responsibility at Johnson & Johnson Pharmaceutical Research & Development LLC (J&JPRD) and Ortho Biotech. Before joining J&J, he served in clinical oncology positions at pharmaceutical companies including Hoffmann-LaRoche, Glaxo Wellcome and Rhone-Poulenc Rorer. He has served as a Member of Medical Advisory Board at Gem Pharmaceuticals, LLC and served as a Director of Ambit Biosciences Corporation.

Dr. Zukiwski holds a bachelor’s degree in pharmacy from the University of Alberta and a MD degree from the University of Calgary. He conducted his post-graduate training at St. Thomas Hospital Medical Center in Akron, Ohio and the University of Texas MD Anderson Cancer Center.

Barbara A. Carlin, MBA, CPA

Barbara A. Carlin, MBA, CPA

Consulting Chief Financial Officer

Barbara Carlin, who is employed by Danforth Advisors LLC, has served as our chief financial officer (CFO) since 2021. Since April 2020, she has been serving as Managing Director, Mid-Atlantic for Danforth Advisors, where she serves as a consultant for life science companies. Prior to joining Danforth Advisors, she served as CFO of Enterin, Inc. from May 2019 to March 2020. She previously held finance leadership roles at Egalet Corporation, Sobi, Inc., Topaz Pharmaceuticals, Inc., Genaera Corporation and Vicuron Pharmaceuticals, Inc. She began her career as an auditor at Deloitte. Barbara is a certified public accountant licensed in the Commonwealth of Pennsylvania and holds a BS in Accounting and MBA in Pharmaceutical and Healthcare Marketing from St. Joseph’s University.

TERMS

Oncolyze
Overview
PRICE PER SHARE
$3.21
DEADLINE
Mar 21, 2024
VALUATION
$29.99M
FUNDING GOAL
$497.55 - $15M
Breakdown
MIN INVESTMENT
$497.55
MAX INVESTMENT
$999,998.46
MIN NUMBER OF SHARES OFFERED
155
MAX NUMBER OF SHARES OFFERED
4,672,897
OFFERING TYPE
Equity
ASSET TYPE
Preferred Stock
SHARES OFFERED
Series A-1 Preferred Stock

Maximum Number of Shares Offered subject to adjustment for bonus shares

*Maximum number of shares offered subject to adjustment for bonus shares. See bonus info below.

Investment Incentives and Bonuses*

Amount-Based Perks:

Tier 1
Invest $1,000+ and receive 2% bonus shares.

Tier 2

Invest $2,500+ and receive 5% bonus shares.

Tier 3

Invest $5,000+ and receive 7% bonus shares.

Tier 4

Invest $10,000+ and receive 10% bonus shares.

NEW UPDATES

05.31.23

We’ve Exceeded $700k+ Funding!

 

 

A picture containing text, screenshot, font, electric blueDescription automatically generated

 

Great news! Oncolyze has surpassed $700k+ in funding through the support of 430+ investors.  This incredible achievement speaks volumes about our team's hard work and the value investors see in our mission.

 

Thank you all for your continued trust and support that contributed to this success. Your investment plays a pivotal role in shaping the future of cancer therapy and bringing hope to patients worldwide.

 

If you haven’t joined our campaign quite yet, now is the perfect time to get behind the company making major strides in the journey to cure cancer.

 

A close-up of a signDescription automatically generated with medium confidence

 

Disclaimer: This investment is speculative, illiquid, and involves a high degree of risk, including the possible loss of your entire investment.

 

ALL UPDATES

05.30.23

Join us in revolutionizing AML treatment - Invest in Oncolyze's StartEngine campaign today!

At Oncolyze, our mission is to transform cancer treatment by developing innovative therapies that target genetic mutations in complex blood cancers like acute myeloid leukemia (AML). 

Our drug, OM-301 (formerly named PNC-27), has shown promising results in animal models with difficult-to-treat mutations such as FLT3, IDH, and TP53. We believe that OM-301's potential to be mutation-agnostic can greatly improve outcomes for AML patients.

With your support in our crowdfunding round, we can advance the development and clinical trials of OM-301, bringing new hope to patients and their families facing limited treatment options and challenging mutations. Together, let's revolutionize AML treatment and make a meaningful impact. Invest in Oncolyze's StartEngine campaign today and support our efforts to develop innovative cancer therapies.

Sources:

1. https://www.cancer.org/cancer/types/acute-myeloid-leukemia.html

2. https://pubmed.ncbi.nlm.nih.gov/31337857/

You should read the Offering Circular (https://lnkd.in/ezWEQbuX) and Risks (https://lnkd.in/e_N2nCtc) related to this offering before investing. This Reg A+ offering is made available through StartEngine Primary, LLC, member FINRA/SIPC. This investment is speculative, illiquid, and involves a high degree of risk, including the possible loss of your entire investment.

05.26.23

Our Community Joins In! | Insider Investment Notice

We're excited to see our community come in and invest in Oncolyze!

Our Insiders have invested a total of $1926  into the offering to date!

We hope you join in as well! Invest in Oncolyze: https://www.startengine.com/offering/oncolyze

 

You should read the Offering Circular (https://lnkd.in/ezWEQbuX) and Risks (https://lnkd.in/e_N2nCtc) related to this offering before investing. This Reg A+ offering is made available through StartEngine Primary, LLC, member FINRA/SIPC. This investment is speculative, illiquid, and involves a high degree of risk, including the possible loss of your entire investment.

 

05.25.23

What is FDA Orphan Drug Designation & Why is it Important?

Orphan Drug Designation (which Oncolyze holds for two indications: acute myeloid leukemia and multiple myeloma) is a regulatory status granted by the U.S. FDA for drugs that are intended to treat rare diseases or conditions. The designation provides several benefits including market exclusivity, tax credits, protocol assistance, and priority review. Market exclusivity provides a significant advantage, as it allows the drug manufacturer, once the drug is approved, to have a period of exclusivity during which no other company can market the same drug for the same indication. The exclusivity period is seven years in the United States (companies may also apply for Orphan Drug Designation even after a drug has already been approved for other uses, extending the life of the drug on the market). For example, If OM-301 has successful clinical trials and receives FDA approval for the treatment of acute myeloid leukemia, having Orphan Drug Designation will insure market protection for OM-301 for this indication.  Along with our mission to bring new treatments to cancer patients, having Orphan Drug Designation is an important part of Oncolyze’s strategy to bring value to investors if our drug is approved.

To learn more about Oncolyze and join us on our mission to bring new treatments to cancer patients by purchasing shares, please click on the following link: https://lnkd.in/epVsHKTZ.

You should read the Offering Circular (https://lnkd.in/ezWEQbuX) and Risks (https://lnkd.in/e_N2nCtc) related to this offering before investing. This Reg A+ offering is made available through StartEngine Primary, LLC, member FINRA/SIPC. This investment is speculative, illiquid, and involves a high degree of risk, including the possible loss of your entire investment.

 

 

 

 

05.23.23

Mark your calendars! 📅 Our first webinar is coming up.

Dear Valued Oncolyze Supporters,

We are immensely grateful for your unwavering support and belief in our mission to revolutionize cancer  treatment.  Your  continuing  investments  have  brought  us  closer  to  achieving  our  goals, and we look forward to sharing our progress with you during the webinar.

We  are  thrilled  to  announce  that  we  will  be  hosting  a  live  webinar  exclusively  for  prospective investors like yourselves. This webinar is scheduled to take place on May 30th at 10am PST and it will provide an in-depth look into Oncolyze's vision, achievements, and future plans. It will be an excellent opportunity for you to gain further insight into our cutting-edge technology and how it has the potential to revolutionize the field of oncology.During the webinar, you will have the chance to hear directly from me, Steve Evans, Co-Founder and  CEO  of  Oncolyze.  I  will  be  going  over  our  body  of  preclinical  data  in  detail,  including  the mechanism of action, more recent findings and thoughts about where Oncolyze will play a role in a very personalized approach to immunotherapy, and the positive impact we aim to make in the lives  of  cancer  patients  worldwide.  It  will  also  be  an  opportunity  to  address  questions  from prospective investors. By attending this webinar, you will:

  • Hear in detail about Oncolyze's latest developments
  • Have the opportunity to engage with the Co-Founder and CEO of Oncolyze
  • Learn how your investment can contribute to the future of cancer treatment

To  secure  your  spot  for  this  informative  session,  please  visit  our  webinar  registration  page.  Spaces  are  limited,  so  we  encourage  you  to  sign  up  as  soon  as possible.

Thank you once again for being an integral part of our journey. Together, we can make a profound difference in the lives of countless individuals battling cancer.

Warm regards,

Steven J. Evans, M.D.

Chief Executive Officer

Oncolyze

05.22.23

Oncolyze Investor Update

Continuing strong momentum in our investor community!

Since our last update a week ago, we have gone from $525k and 300+ investors to over $620k raised and more than 395 investors! It is gratifying to see sharply increasing numbers of investors who are alongside us on our journey.  By purchasing shares in Oncolyze, you can help us progress along our pathway to treat and kill cancer by exploding cancer cells.

To learn more about Oncolyze and join us on our mission to bring new treatments to cancer patients by purchasing shares, please click on the following link: https://lnkd.in/epVsHKTZ.

You should read the Offering Circular (https://lnkd.in/ezWEQbuX) and Risks (https://lnkd.in/e_N2nCtc) related to this offering before investing. This Reg A+ offering is made available through StartEngine Primary, LLC, member FINRA/SIPC. This investment is speculative, illiquid, and involves a high degree of risk, including the possible loss of your entire investment.

05.15.23

Celebrating further steps towards a big goal!

Celebrating further steps towards a big goal! We're happy to share good news on our fundraising efforts on StartEngine – we have raised over $525k from more than 300 investors and still counting!

We are grateful to our growing community for their confidence in us as we continue our journey, and we invite all of you to join us as well. By purchasing shares in Oncolyze, you can help us progress along our pathway to treat and kill cancer by exploding cancer cells.

To learn more about Oncolyze and join us on our mission to bring new treatments to cancer patients by purchasing shares, please click on the following link: https://lnkd.in/epVsHKTZ.

You should read the Offering Circular (https://lnkd.in/ezWEQbuX) and Risks (https://lnkd.in/e_N2nCtc) related to this offering before investing. This Reg A+ offering is made available through StartEngine Primary, LLC, member FINRA/SIPC. This investment is speculative, illiquid, and involves a high degree of risk, including the possible loss of your entire investment.

05.11.23

Learn about screening recommendations from the American Cancer Society

At Oncolyze, we are focused on bringing new treatments to treat cancer.  We also firmly believe that prevention is just as vital as finding new treatments. As part of the larger picture to save as many lives as possible, we feel it is important to follow the existing guidelines for cancer screening and prevention.

The American Cancer Society has screening recommendations for various cancers including  breast, colon and rectal, cervical, endometrial, lung and prostate cancers (source). We encourage you to take an active role in safeguarding your health by learning about these screening recommendations and talking to your doctor. By staying informed and following the guidelines, you can increase the likelihood of early detection, which significantly improves the chances of successful treatment and survival.

Empowered with knowledge and new innovative treatments, we want to make cancer a part of our past!

05.08.23

Scientific Advisory Board Member: Dr. Michael Andreef

Dear Oncolyze community,

 We are excited to introduce you to Dr. Michael Andreeff, another member of our Scientific Advisory Board.

 Dr. Andreeff is an internationally known physician and researcher.   He is Professor of Medicine and holds the Paul and Mary Haas Chair in Genetics at The University of Texas MD Anderson Cancer Center. He has received uninterrupted NCI funding for over 30 years, serves as Principal Investigator of the P01 grant entitled “The Therapy of AML”, participates as Principal Investigator in the MD Anderson Cancer Center Leukemia, Lymphoma, Ovarian and Breast Cancer SPORE grants, the CML P01 and additional R21 and R01 grants. He has published over 639 peer-reviewed papers, 5 books and 75 book chapters. He plays an important role in guiding our clinical and scientific strategy as we work towards our mission of revolutionizing cancer treatment.

Join us in our mission to make a meaningful impact in the fight against cancer. Invest in Oncolyze's StartEngine campaign today and support our efforts to develop innovative cancer therapies.

 P.S. Is there a team member you’d like us to introduce to the community next? Let us know in the comments! 

 Disclaimer: This investment is speculative, illiquid, and involves a high degree of risk, including the possible loss of your entire investment.

 

05.05.23

Scientific Advisory Board Member: Dr. Guido Marcucci

Hello and happy Friday! 

Oncolyze is proud to showcase Dr. Guido Marcucci as one of our esteemed scientific advisors. Dr. Marcucci is a world-renowned hematologist and oncologist with over 30 years of experience in the field. At the City of Hope Comprehensive Cancer Center in Duarte, California Dr. Marcucci serves as: the Chair and Professor, Department of Hematologic Malignancies Translational Science; the Director, Gehr Family Center for Leukemia Research; and Chief, Division of Leukemia. A passionate and dedicated clinician and researcher, he leads multiple clinical trials and research projects aimed at developing new therapies for leukemia and other blood cancers.

His expertise and leadership in the field of hematology and oncology make him an invaluable addition to our Scientific Advisory Board. He brings a wealth of knowledge and experience to our team, and we are excited to be working with him to advance our mission of revolutionizing cancer treatment.

Invest in Oncolyze's StartEngine campaign today and help us develop innovative cancer therapies that have the potential to change the face of cancer treatment.

Thank you,

The Oncolyze Team

P.S. Is there a team member you’d like us to introduce to the community next? Let us know in the comments! 

Disclaimer: This investment is speculative, illiquid, and involves a high degree of risk, including the possible loss of your entire investment.

05.03.23

Investments and Our Community Are Growing!

As of today, we have almost $420k raised, with an ever-increasing number of investors: over 275! 

Thank you to all our investors for your trust and support, and we hope that those of you who are following us will join in as well. 

Please let us know if you have any questions or comments by posting on our discussion board!

With great appreciation,

Dr. Evans

Invest in Oncolyze Today

REWARDS

Multiple investments in an offering cannot be combined to qualify for a larger campaign perk. Get rewarded for investing more into Oncolyze.

$1,000

Tier 1

Invest $1,000+ and receive 2% bonus shares.

$2,500

Tier 2

Invest $2,500+ and receive 5% bonus shares.

$5,000

Tier 3

Invest $5,000+ and receive 7% bonus shares.

$10,000

Tier 4

Invest $10,000+ and receive 10% bonus shares.

JOIN THE DISCUSSION

0/2500

TW
Tom Wright

6 INVESTMENTS

17 days ago

I can't wait to invest in Oncolyze!!, which I plan to do very soon. If this cancer-killing technology is really as good as it looks so far, Oncolyze is going to COMPLETELY REVOLUTIONIZE the treatment of cancer, and hopefully destroy it forever.

1

0













PC
PRABHUDAS CHELUMALA

17 days ago

Hi Oncolyze Team, When does the funding max out. Is it at 1M USD or 14M USD. I want to know as when do you stop accepting funds.

1

0













WL
William Lock

2 months ago

So, how many more pre-clinical steps do you foresee? Are you going to use a model with human disease rather than just implanted cells? How long do you see the pre-clinical phase lasting? What might a treatment regimen look like?

1

2













RM
Ross Morrison

10 INVESTMENTS

2 months ago

I've ridden the AML research investment with Sellas Lifesciences... who is now mid phase 3, focusing on the WT-1 protein for identification.

0

1

CA
Courtney Andrews

2 months ago

I invested in your company on the SeedInvest Platform, with the acquisition, my SeedInvest investment was returned and now the stock is being offered at a higher price. Why couldn't I roll over my investment to StartEngine with the company?

1

0













JH
Justin Horvath

2 months ago

So the deadline is march 21st 2024 to invest in your company on start engine for this offering. Is there any advantage to me investing now in your company compared to me investing march 20th 2024 in your company?

2

1













DM
David Mboh

2 months ago

I have these concerns; 1- if you are at the verge of a breakthrough in cancer treatment through your planned clinical trial for which you claimed this funding round will help finance, don't you think your valuation is questionable? 2- I understand such a company has researchers and most importantly a lot of dedicated folks who aim not just to make history, wealth but also to help people survive deadly cancer and live longer. So what amount of sacrifice they each making making; on a general note, is there anyone on salary in Oncolyze? remember investors sacrifice the same through their heart earned $s 3- I love your mission and really really hopes it works and plan to be part of it hopefully before this raise closes however At what point do you think you may file for chapter 11 or bankruptcy like most startups are doing today? Not looking for anything pleasing here. Just want o know how serious and committed the persons I'm giving my $1 to are. Please do well to respond to my concerns in the best way you can and keep up the good work.

4

0













OT
Oncolyze Team

Oncolyze

2 months ago

Dear W Kim Colich, thank you for your further comments. The offering is fixed for now; if the opportunity arises to change the parameters at some point we will seriously consider your points. Best, Dr. Evans

0

0

WC
W Kim Colich

87 INVESTMENTS

2 months ago

Hi, Why have you not at least offered the SE Owner's Bonus? Especially since you are not offering any early-bird or other time-based bonuses. Thanks. Blessings

2

0













WC
W Kim Colich

87 INVESTMENTS

2 months ago

Hi, I see no mention of any patents for your technology. Please discuss this issue for us all. Thanks. Blessings

2

0













HOW INVESTING WORKS

Cancel anytime before 48 hours before a rolling close or the offering end date.

WHY STARTENGINE?

REWARDS

We want you to succeed and get the most out of your money by offering rewards and memberships!

SECURE

Your info is your info. We take pride in keeping it that way!

DIVERSE INVESTMENTS

Invest in over 200 start-ups and collectibles!

With Regulation A+, a non-accredited investor can only invest a maximum of 10% of their annual income or 10% of their net worth per year, whichever is greater. There are no restrictions for accredited investors.

With Regulation Crowdfunding, non-accredited investors with an annual income or net worth less than $124,000, are limited to invest a maximum of 5% of the greater of those two amounts. For those with an annual income and net worth greater than $124,000, he/she is limited to investing 10% of the greater of the two amounts.

At the close of an offering, all investors whose funds have “cleared” by this time will be included in the disbursement. At this time, each investor will receive an email from StartEngine with their Countersigned Subscription Agreement, which will serve as their proof of purchase moving forward.

Please keep in mind that a company can conduct a series of “closes” or withdrawals of funds throughout the duration of the campaign. If you are included in that withdrawal period, you will be emailed your countersigned subscription agreement and proof of purchase immediately following that withdrawal.

StartEngine assists companies in raising capital, and once the offering is closed, we are no longer involved with whether the company chooses to list shares on a secondary market, or what occurs thereafter. Therefore, StartEngine has no control or insight into your investment after the close of the live offering. In addition, we are not permitted to provide financial advice. You may want to contact a financial professional to discuss possible investment outcomes.

For Regulation Crowdfunding, investors are able to cancel their investment at any point throughout the campaign up until 48 hours before the closing of the offering. Note: If the company does a rolling close, they will post an update to their current investors, giving them the opportunity to cancel during this timeframe. If you do not cancel within this 5-day timeframe, your funds will be invested in the company, and you will no longer be able to cancel the investment. If your funds show as ‘Invested’ on your account dashboard, your investment can no longer be canceled.

For Regulation A+, StartEngine allows for a four-hour cancelation period. Once the four-hour window has passed, it is up to each company to set their own cancelation policy. You may find the company’s cancelation policy in the company’s offering circular.

Once your investment is canceled, there is a 10-day clearing period (from the date your investment was submitted). After your funds have cleared the bank, you will receive your refund within 10 business days.

Refunds that are made through ACH payments can take up to 10 business days to clear. Unfortunately, we are at the mercy of the bank, but we will do everything we can to get you your refund as soon as possible. However, every investment needs to go through the clearing process in order to get sent back to the account associated with the investment.

Both Title III (Regulation Crowdfunding) and Title IV (Reg A+) help entrepreneurs crowdfund capital investments from unaccredited and accredited investors. The differences between these regulations are related to the investor limitations, the differing amounts of money companies are permitted to raise, and differing disclosure and filing requirements. To learn more about Regulation Crowdfunding, click here, and for Regulation A+, click here.

RAISED
$704,518.43
INVESTORS
443
MIN INVEST
$497.55
VALUATION
$29.99M

@ 2022 All Rights Reserved

Apple Store Logo

Get To Know Us

Our Team

Careers

Blog

Important Message

IN MAKING AN INVESTMENT DECISION, INVESTORS MUST RELY ON THEIR OWN EXAMINATION OF THE ISSUER AND THE TERMS OF THE OFFERING, INCLUDING THE MERITS AND RISKS INVOLVED. INVESTMENTS ON STARTENGINE ARE SPECULATIVE, ILLIQUID, AND INVOLVE A HIGH DEGREE OF RISK, INCLUDING THE POSSIBLE LOSS OF YOUR ENTIRE INVESTMENT.


www.StartEngine.com is a website owned and operated by StartEngine Crowdfunding, Inc. (“StartEngine”), which is neither a registered broker-dealer, investment advisor nor funding portal.


Unless indicated otherwise with respect to a particular issuer, all securities-related activity is conducted by regulated affiliates of StartEngine: StartEngine Capital, LLC, a funding portal registered here with the US Securities and Exchange Commission (SEC) and here as a member of the Financial Industry Regulatory Authority (FINRA), or StartEngine Primary, LLC, a broker-dealer registered with the SEC and FINRA/SIPC . You can review the background of our broker-dealer and our investment professionals on FINRA’s BrokerCheck here. StartEngine Secondary is an alternative trading system regulated by the SEC and operated by StartEngine Primary, LLC, a broker dealer registered with the SEC and FINRA. StartEngine Primary, LLC is a member of SIPC and explanatory brochures are available upon request by contacting SIPC at (202) 371-8300.


Investment opportunities posted and accessible through the site are of three types:


1) Regulation A offerings (JOBS Act Title IV; known as Regulation A+), which are offered to non-accredited and accredited investors alike. These offerings are made through StartEngine Primary, LLC (unless otherwise indicated). 2) Regulation D offerings (Rule 506(c)), which are offered only to accredited investors. These offerings are made through StartEngine Primary, LLC. 3) Regulation Crowdfunding offerings (JOBS Act Title III), which are offered to non-accredited and accredited investors alike. These offerings are made through StartEngine Capital, LLC. Some of these offerings are open to the general public, however there are important differences and risks.


Any securities offered on this website have not been recommended or approved by any federal or state securities commission or regulatory authority. StartEngine and its affiliates do not provide any investment advice or recommendation and do not provide any legal or tax advice with respect to any securities. All securities listed on this site are being offered by, and all information included on this site is the responsibility of, the applicable issuer of such securities. StartEngine does not verify the adequacy, accuracy or completeness of any information. Neither StartEngine nor any of its officers, directors, agents and employees makes any warranty, express or implied, of any kind whatsoever related to the adequacy, accuracy, or completeness of any information on this site or the use of information on this site. See additional general disclosures here.


By accessing this site and any pages on this site, you agree to be bound by our Terms of use and Privacy Policy, as may be amended from time to time without notice or liability.


Canadian Investors Investment opportunities posted and accessible through the site will not be offered to Canadian resident investors. Potential investors are strongly advised to consult their legal, tax and financial advisors before investing. The securities offered on this site are not offered in jurisdictions where public solicitation for offerings is not permitted; it is solely your responsibility to comply with the laws and regulations of your country of residence.


California Investors Only – Do Not Sell My Personal Information (800-317-2200). StartEngine does not sell personal information. For all customer inquiries, please write to contact@startengine.com.


StartEngine’s Reg A+ offering is made available through StartEngine Crowdfunding, Inc. This investment is speculative, illiquid, and involves a high degree of risk, including the possible loss of your entire investment. For more information about this offering, please view StartEngine’s offering circular and risk associated with this offering.