We are pleased to announce that a Press Release was published today discussing the exciting, positive, and new discoveries from our ARDS studies.
Here is a sample of what was posted:
PhorMed Inc, a Nevada Corporation (“PhorMed” or the “Company”), is a privately held clinical stage biopharmaceutical company. The Company’s study drug RP-323 is in an on-going acute respiratory distress syndrome (ARDS) study. ARDS is a lung disorder where fluid collects in the air sacs of the lungs, depriving organs of oxygen. These studies have generated positive results showing RP-323 significantly reduces the influx of inflammatory cells into the lungs thereby limiting damage to the lungs. In addition, RP-323 has shown the ability to block over-active/over-productive pro-inflammatory cytokines including the following interleukins: IL-1, IL-2, IL-9 and IL-15. These interleukins have been shown to be key effectors that comprise the “cytokine storm syndrome” (CSS) consistently observed in severe ARDS associated with COVID-19 and other respiratory infections, including influenza and bacterial pneumonia.
ARDS presents in a variety of ways including sudden acute respiratory syndrome (SARS). In severe and fatal ARDS, disease severity is directly associated with the extent of inflammatory cell (neutrophil and macrophage) infiltration into the lungs. When ARDS occurs, these inflammatory cells are profoundly elevated in the blood vessels, alveoli and other lung tissue. This results in congestion, hypoxia, vascular destruction and thrombosis (clotting), swelling, and is reflected in histology in ARDS tissue.
These initial ARDS mouse study results demonstrate that RP-323 safely and effectively reduces pulmonary inflammation. The ARDS animal system that we used is a validated model that is predictive of clinical drug efficacy and widely accepted in the industry. This study therefore represents a milestone advancement towards the Company’s goal of initiating human clinical trials of RP-323 for treating ARDS and COVID-19 related lung disorders.
Expanding on these initial ARDS study results, PhorMed plans to continue its ARDS studies and, in parallel, to further advance its RP-323 human drug development platform by filing a Phase 2 IND application with the USFDA.
About PhorMed Inc:
PhorMed is focused on developing therapies in Oncology, Neurology, and Virology, with initial concentration in treating ARDS induced by COVID-19, AML, Hodgkin’s Lymphoma, Parkinson’s disease, and Stroke. The Company’s goal is to give patients options where there currently are none or allow for better options. PhorMed’s study drug RP-323, or 12-O-tetradecanoylphorbol-13-acetate (TPA) aka Phorbol-12-myristate-13-acetate (PMA), is a treatment administered through I.V. infusion. The RP-323 primary mechanisms of action include (1) induction of differentiation; (2) promotes proliferation; (3) cytokine induction; (4) and/or apoptosis. Find out more at www.PhorMed.com
You can help today by investing and be part of bringing us one step closer to getting an ARDS Phase 2 Human Study underway, sharing our vision of bringing better medical treatment to those in need.
To see the full published article, please click <here>, or search “PHORMED NEWS” on Yahoo Finance.