Oxygen-Enhanced Technology for Advanced Wound Healing and Skin Support

EO2 Concepts is an advanced wound healing technology company leveraging continuous diffusion of oxygen (CDO) therapy to commercialize innovative medical modalities. The company’s primary in-market product is OxyGeni, a wearable device designed to heal wounds to complete closure while simultaneously supporting skin and soft tissue restoration, shortening recovery time, reducing pain, and minimizing the formation of scar tissue in the process.

This Reg CF offering is made available through StartEngine Capital, LLC. This investment is speculative, illiquid, and involves a high degree of risk, including the possible loss of your entire investment.
EO2 Concepts

$418,733.68 Raised


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EO2’s CDO therapy system is an enhanced wound care solution that improves patient outcomes when recovering from chronic wounds, skin injuries, or surgeries. It utilizes the continuous delivery of oxygen directly to the tissue, which has been shown to achieve faster healing, reduced pain levels, and overall improved skin health.*

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EO2’s addressable market encompasses two multibillion dollar divisions. Globally, the chronic wound care sector is estimated to be worth over $20B,*while the aesthetics and cosmetic surgery industry is valued at $63.4B and expected to exhibit nearly double digit CAGR between now and 2030.*

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As an industry innovator, EO2 is focused on continual product testing, research, development, and design, in collaboration with key opinion leaders and medical professionals. Our unique position in an expanding marketplace is secure through 2038, protected by numerous national and international patents, as well as additional patents pending.

*Market information provided by (source) (source) (source)


Advanced Wound Care Therapy Powered By Pure Oxygen

For patients recovering from wounds (i.e. ulcers and burns), amputations, and cosmetic/restorative surgeries, oxygen is one of the most vital elements in the wound-healing process (source). Understanding this, EO2 has developed proprietary technology that allows pure, humidified oxygen to be continuously diffused directly into the tissue, thereby creating an optimal environment for skin repair and restoration. The OxyGeni is an all-inclusive system that offers oxygen generation, wound monitoring, oxygen diffusion dressings, and accessories, all in one lightweight and discrete wearable device.

The Problem & Our Solution

Making CDO Therapy Accessible To Support Wound Healing 24/7

A common obstacle to proper healing of wounds is a lack of oxygen, caused by blocked or damaged blood pathways. Oxygen via the bloodstream is what provides nourishment to the skin and dermal tissues, fueling important processes like collagen formation, cellular regeneration, antibacterial activity, and repair. When the body doesn’t have access to sufficient levels of oxygen, it becomes much harder to carry out these essential functions. However, most existing wound care options involve covering damaged skin, thereby blocking direct flow of oxygen to the tissue.

As a solution, EO2 has developed a system that not only restores oxygen levels, yet also enhances those levels beyond the body’s normal capacity. Using our wearable device, patients receive advanced wound care anywhere, anytime, and are able to accelerate the entire healing process. Additionally, because CDO therapy has benefits for reducing pain and inhibiting the formation of scars, the technology helps to restore quality of life. Positive outcomes from treatment with OxyGeni range from improving aesthetic appearance to preventing amputation.  

The Market & Our Traction

Building a Science-Backed Brand That’s Responsive To An Evolving Market 

Over the last several years, EO2 has been making significant progress across many verticals. In clinical trials, the company’s technology has been substantiated by multiple studies, with peer-reviewed papers published by notable national and international industry leaders. Meanwhile, on the marketing side, we’ve seen mass social media response to the performance of our products for patients, especially in the cosmetic procedures market. 

As a result of our success in these areas, EO2 has seen a robust increase in sales. Within the plastics and aesthetics market, we’ve demonstrated triple-digit YOY growth and in Canada, the company has moved from unpaid trials to payment models in six provinces. By creating products designed to accommodate today’s telehealth models, we are enabling patients to be more involved in their own care through mobile app design, automated product delivery, and AI-driven communication. 

Although EO2 Concepts initially developed solutions for the chronic wound care market, the company has exciting opportunities to expand into other markets based on the science of oxygen therapy’s efficacy and the feedback of medical users. Our newest and fastest-growing market is in aesthetic and reconstructive surgery, as the technology can be used to facilitate healing following face lifts, breast reductions, laser facials, and cosmetic injectables. 

Why Invest

Invest in Proven Technology That Helps People Heal

Chronic wounds affect millions of patients each year and the costs to our healthcare system for diabetic foot complications alone are comparable to all cancers combined (source). Complications from a wound can last months or years, sometimes resulting in amputations, and severely impacting quality of life for patients. Having developed a system that can improve recovery outcomes, in a more accessible and affordable format, EO2’s vision is to bring our technology to the medical community and become the standard of care across multiple segments. Be a part of our success story by investing on Start Engine!

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12500 Network Blvd Ste 310
San Antonio, TX 78249

EO2 Concepts is an advanced wound healing technology company leveraging continuous diffusion of oxygen (CDO) therapy to commercialize innovative medical modalities. The company’s primary in-market product is OxyGeni, a wearable device designed to heal wounds to complete closure while simultaneously supporting skin and soft tissue restoration, shortening recovery time, reducing pain, and minimizing the formation of scar tissue in the process.


Mark Niederauer

Mark Niederauer

President, CEO, Board Member

Dr. Niederauer has served as the Company’s Chief Technology Advisor since June of 2008, has served as the Chief Technology and Operating Officer since January of 2010 and became the President and CEO in August of 2021. He has more than 25 years of experience in commercialization, engineering, product development and manufacturing of pharmaceuticals medical devices, including regulatory and quality compliance. Dr. Niederauer has worked for Bayer Chemikalien in Leverkusen, Germany, Hoechst Celanese in Corpus Christi, TX, and for OsteoBiologics, Inc. (OBI) in San Antonio, TX, which was the acquired by Smith & Nephew Endoscopy. Dr. Niederauer earned a PhD in Biochemical Engineering, with a focus in Genetics, from Iowa State University. He is also a Fulbright Scholar, earning the equivalent of a Master of Science degree from environmental engineering work at the Universität Stuttgart in Germany. Dr. Niederauer has co-authored numerous articles and presentations and is a co-inventor on multiple patents.

Dave Kazynski

Dave Kazynski

Exec. VP of Sales and Marketing, Board Member

Mr. Kazynski is the President of VGM’s HOMELINK business which is a insurance network contractor for a wide range of various healthcare services for members of VGM’s independent Durable Medical Equipment suppliers. HOMELINK has about 110 different managed care contracts. He served many years as a CFO and COO to a number of proprietary hospitals in IA and MO including a hospital sold to Tenet. Mr. Kazynski has been a member on the Center for Medicare Services DME Program Advisory and Oversight Committee (PAOC) and functioned as the hospital liaison for local Managed Care Plans. Mr. Kazynski graduated from the University of Northern Iowa in 1979 with a B.A. in Psychology, and then earned an M.B.A. in Finance in 1981.

Peter Smith

Peter Smith

Chairman of the Board of Directors

Mr Smith served as the Chief Operating Officer of Baxter's Japanese Subsidiary located in Tokyo and later was the President of Baxter's Caremark Division. He founded and led CorSolutions, a disease management company. Subsequently, he also founded and led Medmark, a specialty pharmaceutical distribution business. He currently sits on the Board of four other privately held healthcare companies. Mr Smith received his AB from Princeton University and his MBA from the University of Chicago.

Jim Walsh

Jim Walsh

Board of Directors Member

Jim Walsh is board chairman and general counsel of VGM Group, Inc. As an original investor, Jim has been involved with the company since the late Van G. Miller founded it in 1986. Ten years after his initial investment, Jim became VGM’s corporate counsel, a director of all its companies, and a frequent source and consultant to members of VGM-sponsored companies. Jim is also one of three co-trustees who serve as the governing board for VGM’s Employee Stock Ownership Plan (ESOP).

Jim DeYoung

Jim DeYoung

Board Member

Mr. DeYoung is founder and a principal of Winston Partners Incorporated, which provides strategic corporate advisory and investor relations services to private and public companies. In addition, Mr. DeYoung is a member of the management of DW Investments, LLC. Mr. DeYoung formerly was a general partner of Resource Ventures L.P. He was responsible for several of the fund’s investments. He served at Baxter International, Inc. in marketing, investor relations, public relations and corporate financial management functions. He is a Trustee of Rush University Medical Center and serves on the Executive, Investment and Information Technology Committees of the Board. Mr. De Young serves on a number of boards in the Chicago area. Mr. DeYoung is a graduate of Washington and Lee University (B.A.) and received his J.D. degree from Northwestern University School of Law.

Justin Cypert

Justin Cypert


Mr. Cypert served as the company’s Business Manager since 2009 and became the companies Controller in 2014. He has overall responsibility for business financial operations including treasury, budgeting, forecasting and accounting management. Mr. Cypert has over 20 years of experience in a range of professional areas including manufacturing, business process, financial reporting, audit and compliance. Mr. Cypert has worked for Philips Semiconductors, OsteoBiologics and Smith & Nephew Endoscopy. Mr. Cypert earned his Bachelors in Finance from the University of Texas at San Antonio.

James P. Daley

James P. Daley

Director of Operations

Mr. Daley has over 45 years’ experience in electrical and mechanical engineering, manufacturing and product development in the fields of medical devices and aerospace. He oversees the research, design, manufacturing, packaging and testing of products. Mr. Daley also manages all plant operations, including shipping & receiving and facility maintenance. Mr. Daley is a co-inventor on multiple patents.

Cyndi Gilliam, BSN, RN, FACCWS

Cyndi Gilliam, BSN, RN, FACCWS

Director of Clinical Affairs

Mrs. Gilliam is the Director of Clinical Affairs for EO2. She has worked as an industry Clinical Specialist for the last 10 years, including experience at Kinetic Concepts Inc. Her experience and expertise as a wound care RN has been instrumental in the relationships and educational programs she has built throughout the years. She has excellent contacts across the country within wound care, colorectal surgery, orthopedic, and other specialties. Her passion is integrating her business knowledge with her clinical knowledge to achieve the greatest outcomes for both her patients and clinicians, while achieving success for the company. She is excited to bring her knowledge and skills to help bring EO2 to the forefront of wound care as a standard of care therapy system.

Kate Biasiolli

Kate Biasiolli

Marketing Manager

Mrs. Biasiolli currently holds position as both regional account manager in Texas as well as marketing manager. She has vast experience with in the wound care industry spanning over 15 years. During her tenure at the largest negative pressure wound therapy company, Kinetic Concepts Inc, Mrs. Biasiolli planned, developed and executed customer training throughout the globe while managing her team and million dollar budget. Her honors degree in biology combined with a certificate in adult education provides her a strong background to grasp complex processes and simplify into easy to understand, relatable concepts.

Joseph Monosmith

Joseph Monosmith

Quality Assurance Manager

Mr. Monosmith is the Quality Assurance Manager for EO2, with 13 years of experience in the Medical Device field. He has experience in manufacturing, assembly, shipping/receiving, quality control and quality assurance. In the medical device space, he previously worked in manufacturing and quality for the Endoscopy Division of Smith & Nephew. He is dedicated to, and strongly believes in, the innovation that EO2 brings to wound care, as well as, the positive impact to the quality of life for the patient population.


EO2 Concepts
Apr 11, 2023
Series A Non-Voting Preferred Stock

Maximum Number of Shares Offered subject to adjustment for bonus shares

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Electrochemical Oxygen Concepts, Inc.

Corporate Address


12500 Network Blvd Ste 310, San Antonio, TX 78249

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Series A Non-Voting Preferred Stock

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*Maximum number of shares offered subject to adjustment for bonus shares. See Bonus info below.

Time Based Perks

o First 72 hours – 10% Super Early Bird Bonus

o First week (days 4-7) – 8% Very Early Bird Bonus

o First 3 weeks (week 2 & 3) - 5% Early Bird Bonus

Amount Based Perks

o $600+ – 3% bonus shares , Member, Contributing to enabling advanced healing with oxygen.

o $1,500+ – 5% bonus shares, Leader, Leading the way in oxygen healing solutions.

o $5,000+ – 8% bonus shares, Innovator, Bringing next generation solutions to oxygen delivery and patient monitoring.

o $15,000+ – 10% bonus shares, Visionary, Ensuring the long-term growth and innovation in oxygen solutions for health care. 

Loyalty Bonus - 10% Bonus Shares for Friends and Family 

*In order to receive perks from an investment, one must submit a single investment in the same offering that meets the minimum perk requirement. Bonus shares from perks will not be granted if an investor submits multiple investments that, when combined, meet the perk requirement. All perks occur when the offering is completed.

The 10% StartEngine Owners' Bonus

Electrochemical Oxygen Concepts, Inc. will offer 10% additional bonus shares for all investments that are committed by investors that are eligible for the StartEngine Crowdfunding Inc. OWNer's bonus.

This means eligible StartEngine shareholders will receive a 10% bonus for any shares they purchase in this offering. For example, if you buy 100 shares of Series A Non-Voting Preferred Stock at $1.59/ share, you will receive 110 shares of Series A Non-Voting Preferred Stock, meaning you'll own 110 shares for $159. Fractional shares will not be distributed and share bonuses will be determined by rounding down to the nearest whole share.

This 10% Bonus is only valid during the investor's eligibility period. Investors eligible for this bonus will also have priority if they are on a waitlist to invest and the company surpasses its maximum funding goal. They will have the first opportunity to invest should room in the offering become available if prior investments are canceled or fail.

Investors will receive the highest single bonus they are eligible for among the bonuses based on the amount invested and the time of offering elapsed (if any). Eligible investors will also receive the Owner’s Bonus and an the Loyalty bonus in addition to the aforementioned bonus.

Irregular Use of Proceeds

The Company will not incur irregular use of proceeds.



400K Fundraising Milestone Reached!

Another fundraising milestone met this week! We have now passed $400k and are approaching $450k. If you haven’t had a chance, please take a moment to check out our investment opportunity on StartEngine.

Click on the link to learn more and join us! -


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Meta-analysis Published

Efficacy of Topical Wound Oxygen Therapy in Healing Chronic Diabetic Foot Ulcers: Systematic Review and Meta-Analysis

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Fully Blinded Placebo Study

Continuous diffusion of oxygen improves diabetic foot ulcer healing when compared with a placebo control: a randomised, double-blind, multicentre study

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VIDEO: EO2 on PBS SciTech Now

Featured on PBS SciTech Now on July 14th, 2017, Dr. Mark Niederauer, explains the EO2 Device and CDO Therapy.



New Patent Expanding EO2's Protection Through 2038!

We've had an exciting week at EO2! We were issued our seventh US Patent (patent number 11,529,503). This patent expands on the use of CDO with signals from the wound bed, allowing for wound bed monitoring and adjustments to therapy based on those signals. This patent allowance also expands on the growing number of US and International Patents that provide core patent protection through 2038.

We are excited about the security this brings to the future of CDO Therapy. To learn more or join us, go to:


350K Fundraising Milestone Reached!

We are excited to have reached another fundraising milestone this week! We have now passed $350k and are approaching $400k. If you haven’t had a chance, please take a moment to check out our investment opportunity on StartEngine.

Click on the link to learn more and join us! -


Another Goal Down: 250K Reached!

Another fundraising goal reached! We have now passed $250k and are approaching $300k. If you haven’t had a chance, please take a moment to check out our investment opportunity on StartEngine.

Click on the link to learn more and join us! -


Patient Off Pain Meds in 4 Days After Major Abdominal Surgery

In our latest webinar, Rechelle Trejo, RN describes her personal experience using CDO Therapy for 2 of her own elective surgeries. Rechelle presents her photos and experience after a Lateral Brow Lift where she experienced minimal bruising, no pain and minimal scarring. After her major Abdominalplasty, she was off pain medication within 4 days. 

Listen to Rachelle's full experience here: 

Click on the link to learn more and join us! -


Baylor Study Results: Reduced Wound Size & Increased Tissue Oxygenation for Breast Surgery with CDO

The first results from a Baylor College of Medicine mammoplasty study were presented last week at the 18th Annual Academic Surgical Congress at Baylor College of Medicine. The findings showed that compared to the current standard of care, CDO reduces wound size and significantly increases tissue oxygenation for women undergoing breast surgery.

Clinically these findings would mean a reduction in complications from breast surgeries, which in turn would increase patient satisfaction and save money by minimizing potential revision surgeries.

Excited to see results to even more of the ongoing clinical studies we have! See this study's details here:


Another Goal Met: Approaching $250k!

We are excited to have reached another fundraising goal! We have now passed $200k and are quickly approaching $250k. If you haven’t had a chance yet, please take a moment to check out our investment opportunity on StartEngine.

Click on the link to learn more and join us! -


Notice of Material Change in Offering

[The following is an automated notice from the StartEngine team].

Hello! Recently, a change was made to the EO2 Concepts offering. Here's an excerpt describing the specifics of the change:

Campaign is extending their end date by 60 days

When live offerings undergo changes like these on StartEngine, the SEC requires that certain investments be reconfirmed. If your investment requires reconfirmation, you will be contacted by StartEngine via email with further instructions.


EO2’s International Sales Team Plans for 2023!

Our International Sales Team met this week to exchange ideas and plans for growth in 2023. We had 2 full days packed with exciting ideas. Looking forward to the success for this new year with this team. 

To join our team in our future endeavors and learn more, go to:


American Diabetes Association recommends CDO Therapy as a “Standard of Care” for the treatment of Diabetic Foot Ulcers

The American Diabetes Association (ADA) regularly publishes standards of care and has just added CDO Therapy to their 2023 Standards of Care for the treatment of diabetic foot ulcers.  The ADA article cites recent high level evidence for this decision:

“Topical oxygen therapy has been studied rather vigorously in recent years, with several high-quality RCT’s and at least five systematic reviews and meta-analyses all supporting its efficacy in healing chronic DFU’s at 12 weeks.” Diabetes Care, Volume 46, p. S212, January 2023 

This evidence includes EO2’s study published in the September of 2018 issue of the Journal of Wound Care, cited by CMS as the “Gold Standard” for how studies should be designed.

The ADA Standards of Care article goes on to state:

“Importantly, topical oxygen therapy devices provide for home-based therapy rather than the need for daily visits to specialized centers.” (such as Hyperbaric Oxygen) “Very high participation with very few reported adverse events combined with improved healing rates makes this therapy another attractive option for advanced wound care.”

The physicians who have experienced the significant impact of CDO therapy, including faster healing, reduced scarring and pain, have known that this treatment should be considered the standard of care for most wound types.  Having an independent, clinically oriented organization like the American Diabetes Association make the same recommendation highlights the not only the clinical efficacy, yet also the rapidly growing adoption of CDO therapy as a standard of care.


To learn more and join us, go to:


Behind the Scenes at EO2!

The holidays have ended, and everyone is getting back in the swing of things at EO2. Did you know that EO2 manufactures our own wound dressings and the OxyGeni device? One of our manufacturing technicians, Sisee, is shown here punching tubing, one of the first steps in our dressing assembly.

To join our team in our future endeavors and learn more, go to:

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Multiple investments in an offering cannot be combined to qualify for a larger campaign perk. Get rewarded for investing more into EO2 Concepts.


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This offering is eligible for the StartEngine Owner’s 10% Bonus program. For details on this program, please see the Offering Summary section below.



Invest $600+ and receive 3% Bonus shares



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