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Oxygen-Enhanced Technology for Advanced Wound Healing and Skin Support

EO2 Concepts is an advanced wound healing technology company leveraging continuous diffusion of oxygen (CDO) therapy to commercialize innovative medical modalities. The company’s primary in-market product is OxyGeni, a wearable device designed to heal wounds to complete closure while simultaneously supporting skin and soft tissue restoration, shortening recovery time, reducing pain, and minimizing the formation of scar tissue in the process.

This Reg CF offering is made available through StartEngine Capital, LLC. This investment is speculative, illiquid, and involves a high degree of risk, including the possible loss of your entire investment.

$867,145.97 Raised


EO2’s CDO therapy system is an enhanced wound care solution that improves patient outcomes when recovering from chronic wounds, skin injuries, or surgeries. It utilizes the continuous delivery of oxygen directly to the tissue, which has been shown to achieve faster healing, reduced pain levels, and overall improved skin health.*

EO2’s addressable market encompasses two multibillion dollar divisions. Globally, the chronic wound care sector is estimated to be worth over $20B,*while the aesthetics and cosmetic surgery industry is valued at $63.4B and expected to exhibit nearly double digit CAGR between now and 2030.*

As an industry innovator, EO2 is focused on continual product testing, research, development, and design, in collaboration with key opinion leaders and medical professionals. Our unique position in an expanding marketplace is secure through 2038, protected by numerous national and international patents, as well as additional patents pending.

*Market information provided by (source) (source) (source)


Advanced Wound Care Therapy Powered By Pure Oxygen

For patients recovering from wounds (i.e. ulcers and burns), amputations, and cosmetic/restorative surgeries, oxygen is one of the most vital elements in the wound-healing process (source). Understanding this, EO2 has developed proprietary technology that allows pure, humidified oxygen to be continuously diffused directly into the tissue, thereby creating an optimal environment for skin repair and restoration. The OxyGeni is an all-inclusive system that offers oxygen generation, wound monitoring, oxygen diffusion dressings, and accessories, all in one lightweight and discrete wearable device.

The Problem & Our Solution

Making CDO Therapy Accessible To Support Wound Healing 24/7

A common obstacle to proper healing of wounds is a lack of oxygen, caused by blocked or damaged blood pathways. Oxygen via the bloodstream is what provides nourishment to the skin and dermal tissues, fueling important processes like collagen formation, cellular regeneration, antibacterial activity, and repair. When the body doesn’t have access to sufficient levels of oxygen, it becomes much harder to carry out these essential functions. However, most existing wound care options involve covering damaged skin, thereby blocking direct flow of oxygen to the tissue.


As a solution, EO2 has developed a system that not only restores oxygen levels, yet also enhances those levels beyond the body’s normal capacity. Using our wearable device, patients receive advanced wound care anywhere, anytime, and are able to accelerate the entire healing process. Additionally, because CDO therapy has benefits for reducing pain and inhibiting the formation of scars, the technology helps to restore quality of life. Positive outcomes from treatment with OxyGeni range from improving aesthetic appearance to preventing amputation.  

The Market & Our Traction

Building a Science-Backed Brand That’s Responsive To An Evolving Market 

Over the last several years, EO2 has been making significant progress across many verticals. In clinical trials, the company’s technology has been substantiated by multiple studies, with peer-reviewed papers published by notable national and international industry leaders. Meanwhile, on the marketing side, we’ve seen mass social media response to the performance of our products for patients, especially in the cosmetic procedures market. 

As a result of our success in these areas, EO2 has seen a robust increase in sales. Within the plastics and aesthetics market, we’ve demonstrated triple-digit YOY growth and in Canada, the company has moved from unpaid trials to payment models in six provinces. By creating products designed to accommodate today’s telehealth models, we are enabling patients to be more involved in their own care through mobile app design, automated product delivery, and AI-driven communication. 

Although EO2 Concepts initially developed solutions for the chronic wound care market, the company has exciting opportunities to expand into other markets based on the science of oxygen therapy’s efficacy and the feedback of medical users. Our newest and fastest-growing market is in aesthetic and reconstructive surgery, as the technology can be used to facilitate healing following face lifts, breast reductions, laser facials, and cosmetic injectables. 

Why Invest

Invest in Proven Technology That Helps People Heal

Chronic wounds affect millions of patients each year and the costs to our healthcare system for diabetic foot complications alone are comparable to all cancers combined (source). Complications from a wound can last months or years, sometimes resulting in amputations, and severely impacting quality of life for patients. Having developed a system that can improve recovery outcomes, in a more accessible and affordable format, EO2’s vision is to bring our technology to the medical community and become the standard of care across multiple segments. Be a part of our success story by investing on Start Engine!


12500 Network Blvd Ste 310
San Antonio, TX 78249

EO2 Concepts is an advanced wound healing technology company leveraging continuous diffusion of oxygen (CDO) therapy to commercialize innovative medical modalities. The company’s primary in-market product is OxyGeni, a wearable device designed to heal wounds to complete closure while simultaneously supporting skin and soft tissue restoration, shortening recovery time, reducing pain, and minimizing the formation of scar tissue in the process.


Mark Niederauer

Mark Niederauer

President, CEO, Board Member

Dr. Niederauer has served as the Company’s Chief Technology Advisor since June of 2008, has served as the Chief Technology and Operating Officer since January of 2010 and became the President and CEO in August of 2021. He has more than 25 years of experience in commercialization, engineering, product development and manufacturing of pharmaceuticals medical devices, including regulatory and quality compliance. Dr. Niederauer has worked for Bayer Chemikalien in Leverkusen, Germany, Hoechst Celanese in Corpus Christi, TX, and for OsteoBiologics, Inc. (OBI) in San Antonio, TX, which was the acquired by Smith & Nephew Endoscopy. Dr. Niederauer earned a PhD in Biochemical Engineering, with a focus in Genetics, from Iowa State University. He is also a Fulbright Scholar, earning the equivalent of a Master of Science degree from environmental engineering work at the Universität Stuttgart in Germany. Dr. Niederauer has co-authored numerous articles and presentations and is a co-inventor on multiple patents.

Ken Melani, MD

Ken Melani, MD

Board member

Dr. Melani is currently the owner of KRM Group LLC, a healthcare consulting firm, and managing director of Velocity Fund Partners LLC, a life sciences venture capital fund. He started his career as a practicing Internist where he founded and later became Chairman and CEO of a physician-hospital organization called West Penn Cares. Over the next twenty-five years he served in a variety of executive leadership roles at Highmark Inc, culminating as the President and CEO from 2003-2012. He was credited with growing Highmark into one of the leading healthcare companies in the United States and personally regarded as one of the top healthcare executives in the country. Dr. Melani received his BA from Washington and Jefferson College, where he graduated Summa Cum Laude, and went on to receive a Doctorate of Medicine from The Wake Forest University School of Medicine.

Tony Gallardo

Tony Gallardo

Chief Financial Officer & Secretary

Tony is a Certified Public Accountant with over years of financial and operational experience. He has overall responsibility for business financial operations including treasury, budgeting, forecasting, accounting management and human resources. Tonyhas worked as COO and CFO for entrepreneurial companies in home health care and mental health. With over years of experience Tony is adept at improving processes,including financial reporting, cash flow, internal controls and compliance with contract and regulatory requirements.As a financial leader Tony has extensive experience with budgeting and forecasting. He has guided operational teams to successfully prepare and exceed budgets. Additionally,over his career he has successfully guided the accounting team to set up the internal controls and processes for high growth companies.Tony earned his Bachelors degree in accounting from the University of Texas at SanAntonio. 

Donna Hunt

Donna Hunt

Business Manager and Assistant Secretary

Donna has over 25 years of financial and operational experience in various industries, including medical devices, finance, banking and construction. Donna manages several components of EO2’s business, including accounting, human resources, logistics,document control and facility management. Prior to joining EO2, she worked for a startup medical device company, Bluegrass Vascular Technologies, as the Business Manager until they were recently acquired. Her prior work experience was primarily in banking in various financial and executive support roles for Wells Fargo and Frost Bank.

Dave Kazynski

Dave Kazynski

Exec. VP of Sales and Marketing, Board Member

Mr. Kazynski is the President of VGM’s HOMELINK business which is a insurance network contractor for a wide range of various healthcare services for members of VGM’s independent Durable Medical Equipment suppliers. HOMELINK has about 110 different managed care contracts. He served many years as a CFO and COO to a number of proprietary hospitals in IA and MO including a hospital sold to Tenet. Mr. Kazynski has been a member on the Center for Medicare Services DME Program Advisory and Oversight Committee (PAOC) and functioned as the hospital liaison for local Managed Care Plans. Mr. Kazynski graduated from the University of Northern Iowa in 1979 with a B.A. in Psychology, and then earned an M.B.A. in Finance in 1981.

Peter Smith

Peter Smith

Chairman of the Board of Directors

Mr Smith served as the Chief Operating Officer of Baxter's Japanese Subsidiary located in Tokyo and later was the President of Baxter's Caremark Division. He founded and led CorSolutions, a disease management company. Subsequently, he also founded and led Medmark, a specialty pharmaceutical distribution business. He currently sits on the Board of four other privately held healthcare companies. Mr Smith received his AB from Princeton University and his MBA from the University of Chicago.

Jim DeYoung

Jim DeYoung

Board Member

Mr. DeYoung is founder and a principal of Winston Partners Incorporated, which provides strategic corporate advisory and investor relations services to private and public companies. In addition, Mr. DeYoung is a member of the management of DW Investments, LLC. Mr. DeYoung formerly was a general partner of Resource Ventures L.P. He was responsible for several of the fund’s investments. He served at Baxter International, Inc. in marketing, investor relations, public relations and corporate financial management functions. He is a Trustee of Rush University Medical Center and serves on the Executive, Investment and Information Technology Committees of the Board. Mr. De Young serves on a number of boards in the Chicago area. Mr. DeYoung is a graduate of Washington and Lee University (B.A.) and received his J.D. degree from Northwestern University School of Law.

James P. Daley

James P. Daley

Director of Operations

Mr. Daley has over 45 years’ experience in electrical and mechanical engineering, manufacturing and product development in the fields of medical devices and aerospace. He oversees the research, design, manufacturing, packaging and testing of products. Mr. Daley also manages all plant operations, including shipping & receiving and facility maintenance. Mr. Daley is a co-inventor on multiple patents.

Cyndi Gilliam, BSN, RN, FACCWS

Cyndi Gilliam, BSN, RN, FACCWS

Director of Clinical Affairs

Mrs. Gilliam is the Director of Clinical Affairs for EO2. She has worked as an industry Clinical Specialist for the last 10 years, including experience at Kinetic Concepts Inc. Her experience and expertise as a wound care RN has been instrumental in the relationships and educational programs she has built throughout the years. She has excellent contacts across the country within wound care, colorectal surgery, orthopedic, and other specialties. Her passion is integrating her business knowledge with her clinical knowledge to achieve the greatest outcomes for both her patients and clinicians, while achieving success for the company. She is excited to bring her knowledge and skills to help bring EO2 to the forefront of wound care as a standard of care therapy system.

Kate Biasiolli

Kate Biasiolli

Marketing Manager

Mrs. Biasiolli currently holds position as both regional account manager in Texas as well as marketing manager. She has vast experience with in the wound care industry spanning over 15 years. During her tenure at the largest negative pressure wound therapy company, Kinetic Concepts Inc, Mrs. Biasiolli planned, developed and executed customer training throughout the globe while managing her team and million dollar budget. Her honors degree in biology combined with a certificate in adult education provides her a strong background to grasp complex processes and simplify into easy to understand, relatable concepts.

Joseph Monosmith

Joseph Monosmith

Quality Assurance Manager

Mr. Monosmith is the Quality Assurance Manager for EO2, with 13 years of experience in the Medical Device field. He has experience in manufacturing, assembly, shipping/receiving, quality control and quality assurance. In the medical device space, he previously worked in manufacturing and quality for the Endoscopy Division of Smith & Nephew. He is dedicated to, and strongly believes in, the innovation that EO2 brings to wound care, as well as, the positive impact to the quality of life for the patient population.


EO2 Concepts
Aug 30, 2023
$15k - $1.23M
Preferred Stock
Series A Preferred Stock

Maximum Number of Shares Offered subject to adjustment for bonus shares

Most Recent Fiscal Year-End

Prior Fiscal Year-End

Total Assets



Cash & Cash Equivalents



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Short-Term Debt



Long-Term Debt



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*Maximum number of shares offered subject to adjustment for bonus shares. See Bonus info below.

Time Based Perks

o First 72 hours – 10% Super Early Bird Bonus

o First week (days 4-7) – 8% Very Early Bird Bonus

o First 3 weeks (week 2 & 3) - 5% Early Bird Bonus

Amount Based Perks

o $600+ – 3% bonus shares , Member, Contributing to enabling advanced healing with oxygen.

o $1,500+ – 5% bonus shares, Leader, Leading the way in oxygen healing solutions.

o $5,000+ – 8% bonus shares, Innovator, Bringing next generation solutions to oxygen delivery and patient monitoring.

o $15,000+ – 10% bonus shares, Visionary, Ensuring the long-term growth and innovation in oxygen solutions for health care. 

Loyalty Bonus - 10% Bonus Shares for Friends and Family 

*In order to receive perks from an investment, one must submit a single investment in the same offering that meets the minimum perk requirement. Bonus shares from perks will not be granted if an investor submits multiple investments that, when combined, meet the perk requirement. All perks occur when the offering is completed.

The 10% StartEngine Owners' Bonus

Electrochemical Oxygen Concepts, Inc. will offer 10% additional bonus shares for all investments that are committed by investors that are eligible for the StartEngine Crowdfunding Inc. OWNer's bonus.

This means eligible StartEngine shareholders will receive a 10% bonus for any shares they purchase in this offering. For example, if you buy 100 shares of Series A Non-Voting Preferred Stock at $1.59/ share, you will receive 110 shares of Series A Non-Voting Preferred Stock, meaning you'll own 110 shares for $159. Fractional shares will not be distributed and share bonuses will be determined by rounding down to the nearest whole share.

This 10% Bonus is only valid during the investor's eligibility period. Investors eligible for this bonus will also have priority if they are on a waitlist to invest and the company surpasses its maximum funding goal. They will have the first opportunity to invest should room in the offering become available if prior investments are canceled or fail.

Investors will receive the highest single bonus they are eligible for among the bonuses based on the amount invested and the time of offering elapsed (if any). Eligible investors will also receive the Owner’s Bonus and an the Loyalty bonus in addition to the aforementioned bonus.

Irregular Use of Proceeds

The Company will not incur irregular use of proceeds.


Article Image
Meta-analysis Published

Efficacy of Topical Wound Oxygen Therapy in Healing Chronic Diabetic Foot Ulcers: Systematic Review and Meta-Analysis

Article Image
Fully Blinded Placebo Study

Continuous diffusion of oxygen improves diabetic foot ulcer healing when compared with a placebo control: a randomised, double-blind, multicentre study

Article Image
VIDEO: EO2 on PBS SciTech Now

Featured on PBS SciTech Now on July 14th, 2017, Dr. Mark Niederauer, explains the EO2 Device and CDO Therapy.


Owners bonus
Stack Owner's Bonus & Rewards!

Members get an extra 10% shares in addition to rewards below!


Multiple investments in an offering cannot be combined to qualify for a larger campaign perk. Get rewarded for investing more into EO2 Concepts.



Brian Sims

a month ago

I've already invested and looking to make an additional investment. Why wouldn't CDO be used for all surgeries? Has it been tried for open heart surgery patients that have great scarring? I've been watching and reading about the benefits of CDO and it all looks extremely positive. I can't find anything negative about this. Usually start ups looking for acquisition or IPO. If the latter, any time line?



Patrick Kennedy

a month ago

Gentlemen, Is this really the final raise and if not what will be the valuation next time.?



Richard Koch

3 months ago

I viewed Dr. Armstrong's video. It leaves me with obvious questions about insurance coverage. Who's working the issue of having this therapy covered by insurance? Is a decision close? Have insurance honchos turned their noses up, or is this following the [notionally] logical track to likely approval?



W Kim Colich

4 months ago

Hi Mark, I'm wondering... Do you see potential for your product in the world of sports, i.e. helping athletes perform their absolute best with boosts of oxygen to their tissues? Thanks. Blessings



Christopher Lill

4 months ago

Hello, I would like to know more about your patents ie how many you have and how many pending? Th×



Stephen Hart

4 months ago

Is this system available now?



Terry Dew

5 months ago

What differentiates you from other similar units on the market?



Michael Myers

5 months ago

Exciting technology, I work in the DME industry and have dealt w/NPWT which is a pain both for the patient and the DME, would be interested in considering this as a new product line, especially w/cash options to plastic/reconstructive surgery being a potential customer.



Joseph Russo

6 months ago

This really interested me. As my mother in law had her feet slowly taken off but by bit because she could not heal the area. This would have save her life because she would not have suken into a deep depression that she never came out of. I believe this will save more then time and money in medical costs but the mental health issues related to wounds that don’t heal.



Ronnie Jaikaran

6 months ago

Hello. Is there any tax documents that I need from you for my 2022 filing? Start-up investing is all new to me.




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